Cancer Pharmacology : An Illustrated Manual Of Anticancer Drugs , 2nd Edition (Original PDF From Publisher)
By Judith E. Karp, MD, and Ashkan Emadi, PhD
The visually appealing second edition of Cancer Pharmacology : An Illustrated Manual of Anticancer Drugs provides comprehensive
information on the fundamental and clinical science underlying all licensed, efficient and life-extending cancer medication therapies.
This greatly updated edition offers a practical, bench-to-bedside approach and patient-oriented guide to physicians at all stages of
their careers.
It now places a stronger emphasis on clinical context, application and management in each chapter.
The book offers comprehensive treatment of the fundamental science that is immediately relevant and required at the patient’s
bedside, as well as the significant advancements in cancer pharmacology at the forefront of modern standards of care for solid tumors
and hematologic malignancies.
Along with a new chapter on pharmacogenomics, everything from conventional cytotoxic drugs to targeted genomic, epigenomic,
hormonal and immunotherapeutic agents is studied.
Each chapter provides detailed information on the tumor microenvironment, chemical structures of the drugs, pharmacodynamics,
pharmacokinetics, pharmacogenomic and molecular features of the medications, along with their mechanisms of action, all of which
are elegantly illustrated.
Alkylating drugs, antimetabolites, antimitotics, hormonal agents, targeted therapies, monoclonal antibodies, immunotherapeutic
agents, and many more topics are covered in the book.
This second edition of the book, which was written by top cancer pharmacology experts and extensively updated to reflect new FDA
approved treatments and applications, is still a “must have” for anyone working in the basic, translational or clinical fields of oncology
and hematology, including physicians, pharmacists, nurses and trainees.
Important characteristics :
- Each class of medicines’ architecture, pharmacokinetics, pharmacodynamics and pharmacogenomics are depicted in more than 150 exquisite drawings.
- includes more than 160 chapter review questions in the high-yield hematology and oncology board format (more than twice as many as in the previous version), along with detailed explanations.
- explains the mechanisms of action of immunotherapy, hormonal therapy, targeted therapy and chemotherapy as well as the reasons for their expected use as adjuvants, neoadjuvants and combinations with other forms of treatment.
- Chapters on new FDA drug approvals, disease-site indications, clinical applications and the treatment of medication-drug interactions and toxicities have all been thoroughly updated and improved.
- explains the difficulties in developing new drugs, getting them approved and the legal and regulatory obstacles surrounding anticancer treatments.
- gives crucial background information on pharmacotherapy and includes clinical pearls in every chapter to encourage a bedside, patient-centered approach.
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